Carriers that count

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Multitree automata that count

Multitree are unranked, unordered trees and occur in many Computer Science applications like rewriting and logic, knowledge representation, XML queries, typing for concurrent systems, cryptographic protocols.... We define constrained multitree automata which accept sets of multitrees where the constraints are expressed in a first-order theory of multisets with counting formulas which is very ex...

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Synthetic gene networks that count.

Synthetic gene networks can be constructed to emulate digital circuits and devices, giving one the ability to program and design cells with some of the principles of modern computing, such as counting. A cellular counter would enable complex synthetic programming and a variety of biotechnology applications. Here, we report two complementary synthetic genetic counters in Escherichia coli that ca...

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Gene Silencing Repeats that Count

RIP is nucleus limited. We know this because the specialized cells that carry out RIP are heterokaryotic, with nuclei from both parents. When a sequence is duplicated in one nucleus but not the other, the lone copy is never silenced. The mechanism of RIP is unknown but probably involves DNA:DNA pairing (Figure 1) followed by methyla-Repeated DNA and cytosine methylation are common tion and deam...

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To count and how to count, that is the question.

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Little Things that Count in Transcriptional Regulation

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ژورنال

عنوان ژورنال: Nature Physics

سال: 2020

ISSN: 1745-2473,1745-2481

DOI: 10.1038/s41567-020-0979-5